--- title: Peer Reviewed Research description: Cognome's research leverages real patient data to advance clinical decision support, focusing on perioperative medicine, COVID-19 outcomes, and machine learning innovations across multiple domains. --- [Skip to content](https://cognome.com/peer-reviewed-research#main-content) [![Smarter Safer Secure AI for Healthcare](https://cognome.com/hs-fs/hubfs/Smarter%20Safer%20Secure%20AI%20for%20Healthcare.png?width=2000&height=600&name=Smarter%20Safer%20Secure%20AI%20for%20Healthcare.png)](https://cognome.com/) - AI Governance Show submenu for AI Governance - [AI Sniffer™](https://cognome.com/ai-sniffer) - [ExplainerAI™](https://cognome.com/en-us/explainerai-new) - [Data Services](https://cognome.com/ai-ml-services) Show submenu for Data Services - [OMOP Transforms](https://cognome.com/ai-ml-services) - [Self-Service for Research](https://cognome.com/solutions-for-research) - [AutoChart™ - Quality and Population Health](https://cognome.com/autochart) - Insights Show submenu for Insights - [About](https://cognome.com/our-story) - [Blog](https://cognome.com/blog) - [The Learning Health System Podcast](https://cognome.com/learning-health-system-podcast) - [Published Research](https://cognome.com/peer-reviewed-research) - [Partner Login](https://partners.cognome.com/) Open main navigation Close main navigation - AI Governance Show submenu for AI Governance - [AI Sniffer™](https://cognome.com/ai-sniffer) - [ExplainerAI™](https://cognome.com/en-us/explainerai-new) - [Data Services](https://cognome.com/ai-ml-services) Show submenu for Data Services - [OMOP Transforms](https://cognome.com/ai-ml-services) - [Self-Service for Research](https://cognome.com/solutions-for-research) - [AutoChart™ - Quality and Population Health](https://cognome.com/autochart) - Insights Show submenu for Insights - [About](https://cognome.com/our-story) - [Blog](https://cognome.com/blog) - [The Learning Health System Podcast](https://cognome.com/learning-health-system-podcast) - [Published Research](https://cognome.com/peer-reviewed-research) - [Partner Login](https://partners.cognome.com/) - [Contact us](https://cognome.com/contact-us) [Contact us](https://cognome.com/contact-us) PUBLISHED RESEARCH # Two decades of peer-reviewed research # *From inside the Clinic* Cognome's research traces back to founder Dr. Parsa Mirhaji's earliest work in public health informatics, through the Montefiore Einstein clinical AI program, to the team building Cognome's platform today. Every paper reflects real patients, real data, and real clinical stakes — not benchmarks. # 50+ Peer Reviewed Studies # 7 Clinical & Techical Domains # 10 Issued US Patents ![Publication History](https://cognome.com/hs-fs/hubfs/Publication%20History.jpg?width=2000&height=737&name=Publication%20History.jpg "Publication History") ABOUT THIS RESEARCH Cognome's published research spans seven domains, all grounded in data generated inside real health system environments. The largest body of work covers perioperative medicine and surgical outcomes — machine learning models for predicting case cancellations, prolonged PACU stays, postoperative respiratory failure, and ASA score classification — work that directly informs the clinical decision support tools at the core of Cognome's platform. A substantial portion addresses COVID-19 and infectious disease outcomes from the Montefiore Health System's experience in the Bronx, one of the hardest-hit healthcare environments in the country. More recent work covers oncology AI decision support, pediatric infection prevention, and a fast-growing set of AI & machine learning papers — including sepsis prediction and clinical NLP work co-authored by the Cognome engineering team itself, not just Dr. Mirhaji. Two threads run underneath all of it: health informatics & data platforms — the OMOP/OHDSI infrastructure work that underpins Cognome I/O and Cognome Search — and the foundational public health surveillance research from the team's earliest years in Houston, which is where this all started. All papers (60) Perioperative & Surgical COVID-19 Oncology Pediatrics AI & ML Data Platforms Public Health 2026Apr [Target Trial Emulation of Vaccine Effectiveness in 5- to 17-Year-Olds with Prior SARS-CoV-2 Infection](https://pubmed.ncbi.nlm.nih.gov/41997986/) Yuqing Lei, Jiajie Chen, Qiong Wu, Ting Zhou, ... Parsa Mirhaji, ... Yong Chen, et al. — RECOVER Initiative Nature Communications 2025Oct Symposium Poster [Automated OMOP Concept Mapping Using Multi-Agent Large Language Models and Graph-Enhanced Semantic Retrieval](https://www.ohdsi.org/2025showcase-508/) Adil Ahmed, Selvin Soby, Boudewijn Aasman, Parsa Mirhaji OHDSI 2025 Global Symposium 2025Oct Symposium Poster [Advancing Learning Health Systems Through Integrated Machine Learning](https://www.ohdsi.org/wp-content/uploads/2025/10/313-Aasman_Boudewijn_Integrated-MLOps-OHDSI-Tools_2025symposium-Selvin-Soby.pdf) Boudewijn Aasman, Selvin Soby, Adil Ahmed, Chandra Nelapatla, Manuel Wahle, Parsa Mirhaji OHDSI 2025 Global Symposium 2025Sep [Environment Scan of Generative AI Infrastructure for Clinical and Translational Science](https://doi.org/10.1038/s44401-024-00009-w) Betina Idnay, Zihan Xu, William G. Adams, ... Parsa Mirhaji, ... Hua Xu, Jiang Bian, et al. npj Health Systems 2025Jul [Development of Machine Learning Models to Predict Tumor Endoprosthesis Survival](https://pubmed.ncbi.nlm.nih.gov/40503891/) Barlas Goker, Andrew Brook, Ranxin Zhang, Boudewijn Aasman, Jichuan Wang, Alexander Ferrena, Parsa Mirhaji, et al. Journal of Surgical Oncology 2024Sep [Development of a Natural Language Processing Algorithm for the Detection of Spinal Metastasis Based on MRI Reports](https://pubmed.ncbi.nlm.nih.gov/39149563/) Evan Mostafa, Aaron Hui, Boudewijn Aasman, Kamlesh Chowdary, ... Parsa Mirhaji North American Spine Society Journal 2024Feb [Early Prediction of Onset of Sepsis in Clinical Setting](https://arxiv.org/abs/2402.03486) Fahim Mohammad, Lakshmi Arunachalam, Samanway Sadhu, Boudewijn Aasman, Shweta Garg, Adil Ahmed, Silvie Colman, Meena Arunachalam, Sudhir Kulkarni, Parsa Mirhaji arXiv preprint 2023Dec [Development and Validation of an Instrument to Predict Prolonged Length of Stay in the Postanesthesia Care Unit Following Ambulatory Surgery](https://doi.org/10.1007/s12630-023-02604-1) Samuel Rupp, Elena Ahrens, Maira I. Rudolph, Omid Azimaraghi, ... Parsa Mirhaji, ... Karuna Wongtangman Canadian Journal of Anaesthesia 2023Nov [Development of an Automated, General-Purpose Prediction Tool for Postoperative Respiratory Failure Using Machine Learning](https://pubmed.ncbi.nlm.nih.gov/37422982/) Michael E. Kiyatkin, Boudewijn Aasman, Melissa J. Fazzari, Maíra I. Rudolph, Marcos F. Vidal Melo, Matthias Eikermann, Michelle N. Gong Journal of Clinical Anesthesia 2023Oct [Long-Term Outcomes of COVID-19 Survivors with Hospital AKI: Association with Time to Recovery from AKI](https://doi.org/10.1093/ndt/gfad020) Justin Y. Lu, Montek S. Boparai, Caroline Shi, ... Parsa Mirhaji, Molly C. Fisher, Tim Q. Duong Nephrology Dialysis Transplantation 2023Oct Symposium Poster [Using a Continuous Quality Improvement (CQI) Approach for Gap Analysis of OHDSI/ATLAS as an Enterprise Self-Service Analytics Platform](https://www.ohdsi.org/2023showcase-204/) Selvin Soby, Pavel Goriacko, Jimmy John, Pavan Parimi, Erin M. Henninger, Parsa Mirhaji OHDSI 2023 Global Symposium 2023Oct Symposium Poster [Using OMOP-CDM to Develop Dynamic Disease Registries and Analytic Data Enclaves to Share and Use Real-World Evidence](https://www.ohdsi.org/2023showcase-415/) Erin M. Henninger, Selvin Soby, Manuel Wahle, Boudewijn Aasman, Pavel Goriacko, Chandra Nelapatla, Reetam Nath, Parsa Mirhaji OHDSI 2023 Global Symposium 2023Sep [Association of Reintubation and Hospital Costs and Its Modification by Postoperative Surveillance](https://doi.org/10.1016/j.jclinane.2023.111264) Maíra I. Rudolph, Omid Azimaraghi, Elie Salloum, Lillian J. Wachtendorf, Ahmad Suleiman, Thomas Kammerer, Simon T. Schaefer, Matthias Eikermann, Michael E. Kiyatkin Journal of Clinical Anesthesia 2023Sep [Long Short-Term Memory Model Identifies ARDS and In-Hospital Mortality in Both Non-COVID-19 and COVID-19 Cohort](https://doi.org/10.1136/bmjhci-2023-100782) Jen Ting Chen, Rahil Mehrizi, Boudewijn Aasman, Michelle Ng Gong, Parsa Mirhaji BMJ Health & Care Informatics 2023Sep [Incidence, Characteristics, Risk Factors and Outcomes of Diabetic Ketoacidosis in COVID-19 Patients](https://doi.org/10.1111/dom.15120) Kevin Dell’Aquila, Jeylin Lee, Stephen H. Wang, ... Parsa Mirhaji, Wei Hou, Kevan C. Herold, Tim Q. Duong Diabetes, Obesity and Metabolism 2023Aug [Development and Validation of a Machine Learning ASA-Score to Identify Candidates for Comprehensive Preoperative Screening and Risk Stratification](https://doi.org/10.1016/j.jclinane.2023.111103) Karuna Wongtangman, Boudewijn Aasman, Shweta Garg, Annika S. Witt, Arshia A. Harandi, Omid Azimaraghi, Parsa Mirhaji, Selvin Soby, Preeti Anand, Carina P. Himes, Richard V. Smith, Peter Santer, Jeffrey Freda, Matthias Eikermann, Priya Ramaswamy Journal of Clinical Anesthesia 2023Apr [Characteristics of COVID-19 Patients with Multiorgan Injury Across the Pandemic in a Large Academic Health System in the Bronx, New York](https://doi.org/10.1016/j.heliyon.2023.e15277) Justin Y. Lu, Alexandra Buczek, Roman Fleysher, ... Chandra Nelapatla, Selvin Soby, Parsa Mirhaji, ... Tim Q. Duong Heliyon 2023Feb [Comparison of the Effects of Sugammadex Versus Neostigmine for Reversal of Neuromuscular Block on Hospital Costs of Care](https://doi.org/10.1016/j.bja.2022.10.015) Luca J. Wachtendorf, Tim M. Tartler, Elena Ahrens, ... Parsa Mirhaji, ... Matthias Eikermann British Journal of Anaesthesia 2022Dec [Incidence and Predictors of Case Cancellation Within 24h in Patients Scheduled for Elective Surgical Procedures](https://doi.org/10.1016/j.jclinane.2022.110987) Karuna Wongtangman, Omid Azimaraghi, Jeffrey Freda, ... Parsa Mirhaji, ... Matthias Eikermann Journal of Clinical Anesthesia 2022Nov [OpenFL: The Open Federated Learning Library](https://doi.org/10.1088/1361-6560/ac97d9) Patrick Foley, Micah J. Sheller, Brandon Edwards, ... Parsa Mirhaji, Prashant Shah, Spyridon Bakas Physics in Medicine & Biology 2022Oct Symposium Poster [Einstein-ATLAS: Leveraging OHDSI/ATLAS and Open-Source Development to Support Translational Research, Data Science, and Regulatory Compliance](https://www.ohdsi.org/2022showcase-14/) Parsa Mirhaji, Selvin Soby, Erin Henninger, Chandra Nelapatla, Manuel Wahle, Boudewijn Aasman, Eran Bellin OHDSI 2022 Global Symposium 2022Oct Symposium Poster [Data Quality Monitoring, Transparency and Governance: Enterprise Process for Data Quality Stewardship and Governance for Real-World Data](https://www.ohdsi.org/2022-collaborator-showcase/) Parsa Mirhaji, Selvin Soby, Erin Henninger, Chandra Nelapatla, Manuel Wahle, Boudewijn Aasman, Eran Bellin OHDSI 2022 Global Symposium 2022Sep [Entity Event Knowledge Graph for Powerful Health Informatics](https://doi.org/10.1109/ICHI54592.2022.00068) Ravi Bajracharya, Richard Wallace, Jans Aasman, Parsa Mirhaji IEEE ICHI 2022Aug [Pediatric Surgical Site Infection (SSI) Following Ambulatory Surgery: Incidence, Risk Factors and Patient Outcomes](https://doi.org/10.1017/ice.2021.279) Michael L. Rinke, David G. Bundy, Moonseong Heo, ... Parsa Mirhaji, ... Suzette O. Oyeku Infection Control & Hospital Epidemiology 2022Jul [Epidemiology of Organ Failure Before and During COVID-19 Pandemic Surge Conditions](https://doi.org/10.4037/ajcc2022990) James Brogan, Melissa Fazzari, Kaitlyn Philips, Boudewijn Aasman, Parsa Mirhaji, Michelle Ng Gong American Journal of Critical Care 2022Jun [Improving Adjuvant Liver-Directed Treatment Recommendations for Unresectable Hepatocellular Carcinoma: An AI-Based Decision-Making Tool](https://doi.org/10.1200/CCI.22.00024) Allen Mo, Christian Velten, Julie M. Jiang, ... Parsa Mirhaji, Kei Nemoto, Boudewijn Aasman, ... Rafi Kabarriti JCO Clinical Cancer Informatics 2021Dec [Central Venous Catheter Salvage in Ambulatory Central Line-Associated Bloodstream Infections](https://doi.org/10.1542/peds.2020-042069) William J.H. Ford, David G. Bundy, Suzette Oyeku, ... Parsa Mirhaji, ... Michael L. Rinke Pediatrics 2021Nov [Clinical Characteristics of the First and Second COVID-19 Waves in the Bronx, New York: A Retrospective Cohort Study](https://doi.org/10.1016/j.lana.2021.100041) Wouter S. Hoogenboom, Antoine Pham, Harnadar Anand, ... Selvin Soby, Parsa Mirhaji, Judy Yee, Tim Q. Duong The Lancet Regional Health — Americas 2021Nov [Individuals with Sickle Cell Disease and Sickle Cell Trait Demonstrate No Increase in Mortality or Critical Illness from COVID-19](https://doi.org/10.3324/haematol.2021.279222) Wouter S. Hoogenboom, Roman Fleysher, Selvin Soby, Parsa Mirhaji, William B. Mitchell, Kerry A. Morrone, Deepa Manwani, Tim Q. Duong Haematologica 2021Jan [Pediatric Ambulatory Central Line-Associated Bloodstream Infections](https://doi.org/10.1542/PEDS.2020-0524) Michael L. Rinke, Moonseong Heo, Lisa Saiman, ... Parsa Mirhaji, ... Suzette O. Oyeku Pediatrics 2020Nov [Costs of Ambulatory Pediatric Healthcare-Associated Infections: CLABSIs, CAUTIs, and Surgical Site Infections](https://doi.org/10.1017/ice.2020.305) Michael L. Rinke, Suzette O. Oyeku, William J.H. Ford, ... Parsa Mirhaji, ... David G. Bundy Infection Control & Hospital Epidemiology 2020Aug [Pediatric Ambulatory Catheter-Associated Urinary Tract Infections (CAUTIs): Incidence, Risk Factors, and Patient Outcomes](https://doi.org/10.1017/ice.2020.204) Michael L. Rinke, Suzette O. Oyeku, Moonseong Heo, ... Parsa Mirhaji, ... David G. Bundy Infection Control & Hospital Epidemiology 2018Oct [Multicenter Derivation and Validation of an Early Warning Score for Acute Respiratory Failure or Death in the Hospital](https://doi.org/10.1186/s13054-018-2194-7) Mikhail A. Dziadzko, Paul J. Novotny, Jeff Sloan, Ognjen Gajic, Vitaly Herasevich, Parsa Mirhaji, Yiyuan Wu, Michelle Ng Gong Critical Care 2018Aug [Leveraging Electronic Health Records for Clinical Research](https://doi.org/10.1016/j.ahj.2018.04.015) Sudha R. Raman, Lesley H. Curtis, Robert Temple, ... Parsa Mirhaji, ... Adrian F. Hernandez American Heart Journal 2018Jan [Knowledge Graph Solutions in Healthcare for Improved Clinical Outcomes](http://www.scopus.com/inward/record.url?scp=85055330981&partnerID=8YFLogxK) Jans Aasman, Parsa Mirhaji ISWC (P&D/Industry/BlueSky) 2017  [The Good, The Bad, and The Ugly of Deploying and Adopting Machine Learning Based Models in Clinical Practice](http://knowledge.amia.org/65881-amia-1.3897810/t002-1.3901961/f002-1.3901962/2731728-1.3902087/2732179-1.3902084) Yin Aphinyanaphongs, David Holmes, Berkman Sahiner, Parsa Mirhaji, Michael Draugelis AMIA Annual Symposium 2016Nov [Preserving Temporal Relations in Clinical Data While Maintaining Privacy](https://doi.org/10.1093/jamia/ocw001) George Hripcsak, Parsa Mirhaji, Alexander F.H. Low, Bradley A. Malin Journal of the American Medical Informatics Association 2016Jun [Early Intervention of Patients at Risk for Acute Respiratory Failure and Prolonged Mechanical Ventilation: Protocol for PROOFCheck](https://doi.org/10.1136/bmjopen-2016-011347) M. N. Gong, L. Schenk, O. Gajic, P. Mirhaji, J. Sloan, Y. Dong, E. Festic, V. Herasevich BMJ Open 2014  [Changing the Research Landscape: The New York City Clinical Data Research Network](https://doi.org/10.1136/amiajnl-2014-002764) Rainu Kaushal, George Hripcsak, Deborah D. Ascheim, ... Parsa Mirhaji, Harold A. Pincus, et al. Journal of the American Medical Informatics Association 2013  [Ontology-Based Entity Extraction of Quality Metrics from Narrative Texts](https://knowledge.amia.org/amia-55142-a2013e-1.580047/t-06-1.582200/f-006-1.582201/a-321-1.583025/a-323-1.583019) Sina Madani, Dean F. Sittig, Hua Xu, Parsa Mirhaji, Kim Dunn, Reza Alemy AMIA Annual Symposium 2012Apr [Coordination and Management of Multicenter Clinical Studies in Trauma: Experience from PROMMTT](https://doi.org/10.1016/j.resuscitation.2011.09.019) Mohammad H. Rahbar, Erin E. Fox, Deborah J. del Junco, ... Parsa Mirhaji, ... John B. Holcomb Resuscitation 2011  [Quality of Care Domain Modeling in Cancer: A Semantic Approach](http://www.scopus.com/inward/record.url?scp=84891924095&partnerID=8YFLogxK) Sina Madani, Dean F. Sittig, Parsa Mirhaji, Kim Dunn International Conference on Biomedical Ontology 2009Jun [Public Health Surveillance Meets Translational Informatics: A Desiderata](https://doi.org/10.1016/j.jala.2009.02.007) Parsa Mirhaji Journal of Laboratory Automation 2009  [Ontology Driven Integration Platform for Clinical and Translational Research](https://doi.org/10.1186/1471-2105-10-S2-S2) Parsa Mirhaji, Min Zhu, Mattew Vagnoni, Elmer V. Bernstam, Jiajie Zhang, Jack W. Smith BMC Bioinformatics 2009  [Biomedical Language Understanding and Extraction (BLUE-Text): A Minimal Syntactic, Semantic Method](https://digitalcommons.library.tmc.edu/uthshis_dissertations/13/) Parsa Mirhaji — PhD Dissertation, advised by Jiajie Zhang UTHealth School of Biomedical Informatics 2008  [Semantic Representation of CDC-PHIN Vocabulary Using Simple Knowledge Organization System](http://www.scopus.com/inward/record.url?scp=73949086499&partnerID=8YFLogxK) Min Zhu, Parsa Mirhaji AMIA Annual Symposium 2007May [Improving the Public Health Information Network Through Semantic Modeling](https://doi.org/10.1109/MIS.2007.53) Parsa Mirhaji, S. Ward Casscells, Dean Allemang, Robert Coyne IEEE Intelligent Systems 2006  [Information Integration from Heterogeneous Data Sources: A Semantic Web Approach](http://www.scopus.com/inward/record.url?scp=34748903419&partnerID=8YFLogxK) Narendra Kunapareddy, Parsa Mirhaji, David Richards, S. Ward Casscells AMIA Annual Symposium 2006  [Semantic Approach for Text Understanding of Chief Complaints Data](http://www.scopus.com/inward/record.url?scp=34748895412&partnerID=8YFLogxK) Parsa Mirhaji, Sean Byrne, Narendra Kunapareddy, S. Ward Casscells AMIA Annual Symposium 2006  [Semantic Web Representation of LOINC: An Ontological Perspective](http://www.scopus.com/inward/record.url?scp=34748907782&partnerID=8YFLogxK) Arunkumar Srinivasan, Narendra Kunapareddy, Parsa Mirhaji, S. Ward Casscells AMIA Annual Symposium 2006  [Services Oriented Architectures and Rapid Deployment of Ad-Hoc Health Surveillance Systems: Lessons from Katrina Relief Efforts](http://www.scopus.com/inward/record.url?scp=34748899988&partnerID=8YFLogxK) Parsa Mirhaji, S. Ward Casscells, Arunkumar Srinivasan, Narendra Kunapareddy, Sean Byrne, David Mark Richards, Raouf Arafat AMIA Annual Symposium 2005  [A Web Services Architecture for UMLS Knowledge Sources](http://www.scopus.com/inward/record.url?scp=39049182392&partnerID=8YFLogxK) Parsa Mirhaji, Narendra Kunapareddy, Yanko Michea, Arunkumar Srinivasan AMIA Annual Symposium 2005  [Information Visualization for Quality Control in Health Data Exchange Platforms](http://www.scopus.com/inward/record.url?scp=39049194273&partnerID=8YFLogxK) Narendra Kunapareddy, Parsa Mirhaji, Jiajie Zhang, Yanko Michea, Arunkumar Srinivasan AMIA Annual Symposium 2005  [Situational Awareness in Public Health Preparedness Settings](https://doi.org/10.1117/12.607114) Parsa Mirhaji, Yanko F. Michea, Jiajie Zhang, Samuel W. Casscells SPIE Defense, Security & Sensing 2005  [Houston Biosecurity: Building a National Model](http://www.scopus.com/inward/record.url?scp=63549129362&partnerID=8YFLogxK) Parsa Mirhaji, Yanko F. Michea, Jiajie Zhang, Samuel W. Casscells SPIE Defense, Security & Sensing 2004  Knowledge Based Public Health Situation Awareness Parsa Mirhaji, Jiajie Zhang, Arunkumar Srinivasan, Rachel L. Richesson, Jack W. Smith Conference paper 2004  [Public Health Situation Awareness, Towards a Semantic Approach](https://doi.org/10.1117/12.541189) Parsa Mirhaji, Rachel L. Richesson, James P. Turley, Jiajie Zhang, Jack W. Smith SPIE Defense, Security & Sensing 2003Jul [Influenza as a Bioweapon](https://doi.org/10.1258/jrsm.96.7.345) Mohammad Madjid, Scott Lillibridge, Parsa Mirhaji, Ward Casscells Journal of the Royal Society of Medicine 2003  [Informatics Critical to Public Health Surveillance](https://doi.org/10.1117/12.500842) Parsa Mirhaji, Jiajie Zhang, Jack W. Smith, Mohammad Madjid, Samuel W. Casscells, Scott R. Lillibridge SPIE Defense, Security & Sensing 2003  [Preparing Houston: Lessons Learned, Future Directions](https://doi.org/10.1117/12.517220) Mohammad Madjid, Parsa Mirhaji, Scott Lillibridge, Ward Casscells SPIE Defense, Security & Sensing - [AI Sniffer](https://cognome.com/ai-sniffer) - [OMOP Transforms](https://cognome.com/ai-ml-services) - [Self Service for Research](https://cognome.com/solutions-for-research) - [AutoChart](https://cognome.com/autochart) - [Privacy Policy](https://cognome.com/en-us/privacy-policy) **COGNOME** - *Smarter, Safer, Secure AI for Healthcare*.  Follow us on [Linked In](https://www.linkedin.com/company/cognome) 800 N King Street, Suite 304 1586, Wilmington DE 19801 USA. © 2018-2026 Cognome, Inc. All rights reserved